International Journal of Anatomical Sciences 2013, 4(1): 29-34

Research Paper

 Study of Holoprosencephaly

Melani Rajendran S, Venkatasai PM.

Dept. of Anatomy, Matha Dental College and Hospital, Chennai – 600 069, Tamil Nadu, India.
Dept. of Radiology and Imaging Sciences, Sri Ramachandra Medical College and Research Institute, Chennai – 600 116, Tamil Nadu, India.

Key Words:holoprosencephaly, alobar holoprosencephaly, semilobar holoprosencephaly, lobar holoprosencephaly, neural tube defect

Abstract:Holoprosencephaly is a rare congenital brain malformation that occurs during development due to incomplete separation of the cerebral hemispheres .It may be caused due to hereditary factors, chromosomal anomalies, environmental teratogenic factors. Four cases of holoprosencephaly were observed during a period of one year and their features are discussed.